Additionally, CSCs enhance immunosuppression simply by down-regulation of major histocompatibility complex MHC-I and -II (a milieu of proteins that regulate cell-mediated adaptive response) and through the discharge of immunosuppressive cytokines such as for example IL-10 and TGF[60,61,81,82]
Additionally, CSCs enhance immunosuppression simply by down-regulation of major histocompatibility complex MHC-I and -II (a milieu of proteins that regulate cell-mediated adaptive response) and through the discharge of immunosuppressive cytokines…