DPP-IV

Targeting PI3K signalling in tumor: opportunities, limitations and challenges

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Targeting PI3K signalling in tumor: opportunities, limitations and challenges. Immunohistochemical assay for tumor tissues microarrays of lung tumor tissue demonstrated that BPTF overexpression forecasted an unhealthy prognosis in the sufferers…

Continue ReadingTargeting PI3K signalling in tumor: opportunities, limitations and challenges

Concentrations used: 1, 50 nmol/L; Gemcitabine, 50 nmol/L; Paclitaxel, 5 Staurosporine and nmol/L, 1 mol/L

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Concentrations used: 1, 50 nmol/L; Gemcitabine, 50 nmol/L; Paclitaxel, 5 Staurosporine and nmol/L, 1 mol/L. repairing p53 to activate mitochondrial-apoptotic pathways (i.e., cytochrome c launch, caspase activation and PARP cleavage).…

Continue ReadingConcentrations used: 1, 50 nmol/L; Gemcitabine, 50 nmol/L; Paclitaxel, 5 Staurosporine and nmol/L, 1 mol/L